On Lucretius’s poem about Epicurean science: On the Nature of Things aka De Rerum Natura from the first century BCE.
How does the world work? Lucretius presents a system that is surprisingly modern, and raises philosophical issues that are still on point today: What are the basic building blocks of the universe? How could these give rise to minds? What ethical views does a mechanistic worldview imply?
Keep an eye out for the follow-up discussion where Mark and Wes go into more details from the text.